Penis Sensitivity with Substance P: Controlling His Pleasure Levels

Let’s talk about penis sensitivity. Some men wish they could feel more—like every little touch, lick, or tease is an electric jolt of pleasure. Others? They wish they could feel less, because finishing too soon can be frustrating (for both of you). And then, of course, there’s us women—who, if we’re being honest, generally wish he could last just a little bit longer.

If you’re in a female-led relationship, male chastity dynamic, or just love experimenting in the bedroom, understanding how to manipulate sensitivity is an absolute game-changer. And one of the biggest keys to this? Substance P.

What Is Substance P (SP)?

Substance P is a neuropeptide (a fancy way of saying a small protein that affects the nervous system). It plays a major role in pain, pleasure, and sexual sensitivity by controlling how nerves communicate. My neurobiology classes are paying off with today’s blog. When you have more Substance P, nerve endings become hypersensitive, making touch feel more intense. When you have less Substance P, nerve endings are numbed and less responsive, meaning a man can last much longer before orgasm. I’m sure others could do a much better job of describing what Substance P is but for the purposes of this blog I’ll leave it at that.

Think of it as a pleasure dial—more Substance P = more sensitivity, less Substance P = more control. And guess what? Controlling him can be fun.

Capsaicin: The Magic Lever for Controlling Penis Sensitivity

Capsaicin is the active compound in chili peppers that makes spicy food burn. It directly interacts with the vanilloid receptors in nerve endings, which control heat, pain, and (most importantly) sensitivity. When applied topically in small amounts, capsaicin temporarily blocks Substance P, creating an effect that’s like turning up the volume on sensation. When taken internally (like in food or supplements), capsaicin actually depletes Substance P over time, leading to a long-term reduction in sensitivity.

So depending on how you use it, capsaicin can either boost his penis sensitivity for a night of fun, or train him to last longer over time.

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Increase Penis Sensitivity With Substance P

If you want him to feel every single touch, making him moan, squirm, and beg for more, these are the best ways to increase Substance P:

1. Capsaicin Cream (Temporary Penis Sensitivity Boost)
   • Applying a very small amount (pea size or smaller) of capsaicin-based cream directly to the penis about 15-20 minutes before play can make him insanely sensitive.
   • External use only – Keep the cream away from his pee pee hole.
   • Wait about 5 minutes and wash your hands and the entirely area thoroughly with soap and water.
   • This works by temporarily blocking Substance P and activating nerve endings.
   • The effect lasts a few hours, making it perfect for an edging session or a special tease-and-denial night.
   • Be careful and start with a very small amount, too much will burn. Think of it like Icy Hot—but on his most sensitive area. Not fun if you use too much.
2. Short-Term Alcohol Use
   • A glass of wine or a cocktail can temporarily increase nerve sensitivity and blood flow. Just don’t overdo it—long-term alcohol use has the opposite effect (more on that below).
3. Exercise & Blood Circulation
   • More blood flow = more Substance P. Regular cardio and strength training can naturally increase nerve sensitivity over time.
4. Abstaining from Spicy Foods
   • Since capsaicin depletes Substance P over time, cutting out spicy foods for a while can naturally make him more sensitive in bed.
5. Teasing, Edging & Chastity Play
   • The longer he’s denied, the more sensitive he becomes. Keeping him locked for days naturally build up nerve sensitivity, making every touch feel mind-blowing when you finally set him free.

I picked this generic capsaicin cream that did the job perfectly, but really, any cream with capsaicin should work as long as you’re checking the label. You want to get a low dosage, 0.025% is plenty and be sure to avoid anything with lidocaine or menthol. Creams with too many additives can potentially cause irritation or reduce the effectiveness, I have sensitive skin so I always read labels carefully.

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Decrease Penis Sensitivity With Substance P

If he’s finishing too quickly, or if you want to train him to last longer, you’ll want to decrease Substance P over time. Here’s how:

1. Capsaicin Supplements or Spicy Foods
   • Taking capsaicin supplements daily or eating spicy foods regularly will slowly deplete Substance P, leading to reduced sensitivity over time.
   • This is perfect for men who struggle with premature ejaculation or just want to increase stamina.
2. Long-Term Alcohol Use (Not Recommended)
   • Chronic alcohol consumption lowers Substance P over time, leading to numbness. (Obviously, this isn’t the healthiest option, but it’s a known effect.)
3. Cold Therapy
   • Applying cold (like a cool compress) before sex can reduce nerve sensitivity temporarily, which can help with lasting longer.
4. Numbing Creams
   • Creams with lidocaine or benzocaine are designed to temporarily dull sensation, giving more control.
5. Deep Breathing & Mindfulness
   • Sensitivity isn’t just physical—it’s mental. Training the mind to slow down arousal through meditation or tantric techniques can naturally reduce overstimulation.

I did not purchase this one but here is an example of a capsaicin supplement which should deliver a sufficient amount of capsaicin without unnecessary fillers or additives. Any quality supplement should work, just be sure that it clearly lists the capsaicin content on the label. A higher-quality supplement will focus on natural ingredients and avoid additives, artificial colors that can interfere with your body’s absorption.

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Delayed Ejaculation and Substance P

Delayed ejaculation (DE) is when a guy has trouble reaching orgasm, even after lots of sexual stimulation. It can happen for a variety of reasons, like nerve problems, stress, anxiety, or taking certain medications like antidepressants. Other health issues, such as diabetes or hormone imbalances, can also make things harder. On the mental side, if a guy is feeling pressured or anxious about sex, that can slow things down too. An increase in Substance P can make him more sensitive and remove that orgasm delay.

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Premature Ejaculation and Substance P

Premature ejaculation (PE) happens when a guy ejaculates too quickly during sex, often before he or his partner is ready. It can be caused by both mental and physical factors. Mentally, stress, anxiety, or worrying about performance can cause the body to react too quickly. Physically, things like hormonal imbalances or sensitive nerves can make a man ejaculate faster than he wants to. It’s usually a mix of both mental and physical issues that causes PE.

When there’s too much Substance P, it can make the body feel overly sensitive, causing orgasm to happen too soon. If you lower the levels of Substance P, the body becomes less sensitive, which helps delay ejaculation and gives a man more control during sex.

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Erectile Dysfunction and Substance P

When a man becomes aroused, nerves send signals to the penis to increase blood flow, which leads to an erection. But if there’s too much Substance P, the nerves can become too sensitive or even overactive. This means the body might not respond the right way, leading to problems with maintaining an erection or getting too excited too quickly, which can cause erectile dysfunction. Essentially, high levels of Substance P can throw off the balance needed for normal penis go up and penis go down function (scientific terms).

Lowering Substance P levels may help improve erectile dysfunction. By reducing the amount of this chemical, the nervous system calms down and can respond to sexual stimulation more normally. This can help with both getting and keeping an erection.

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Why Have I Never Heard of Substance P?

Even though Substance P plays a huge role in how we feel sensations, it’s not something that typically gets brought up in everyday conversations. Most of us know about things like endorphins (those “feel-good” chemicals) or dopamine (the reward chemical), but Substance P is a little more under the radar. It’s effects aren’t as commonly researched and hidden in the more specialized areas of neurobiology or pain research, which is why it doesn’t get the same spotlight.

I fell into the research rabbit hole on this one and did WAY too much research but I wanted to keep this blog to a reasonable length so if you have questions, please ask below, I might know a little bit more than I’ve let on so far.

Substance P is a fun tool for penis sensitivity. Use it carefully, and have fun. 😉

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Evolving Your Conversation

1. If you could control your partner’s sensitivity like a dial, what setting would you put him on?
2. Have you ever experimented with sensation play? What worked (or didn’t)?
3. Would you rather tease him to the point of hypersensitivity or train him to last as long as you want?